Nocturnal circulating tumor cells: The ultimate selective filter in cancer progression?

Authors: Frédéric Thomas, Antoine M. Dujon, Beáta Újvári, Catherine Alix-Panabières

Source: Med (Aug 2022)


The survival duration of circulating tumor cells (CTCs) in the vasculature is a critical parameter in the establishment of the metastatic cascade.

Diamantopoulou and colleagues demonstrate that the metastatic capacity of CTCs is strongly influenced by circadian rhythms, suggesting a rationale for the time-controlled interrogation and treatment of metastatic cancers.