Could a discovery of several antibodies, that seem to fight off the disease, stop the parasitic cancer wiping out Tasmanian devils?

Tasmanian DevilResearchers have been desperately trying to develop treatments against the disease, but despite some promising progress towards a vaccine, for the most part, study after study has come back with nothing but bad news.

Could ‘active immunotherapy’ be the solution? Read more on this via ScienceAlert.com and find out what  lead researcher Beata Ujvari, from Deakin University in Australia has to say.

More info can also be found via:

  1. Deakin Media: Natural antibodies could combat Tasmanian devil cancer
  2. Nature – Scientific Reports: Immunoglubolin dynamics and cancer prevalence in Tasmanian devils

Predictable evolution: bad news for toads, good news for their predators | @GrrlScientist http://gu.com/p/4c628/stw

Beautiful summary of our work by @GrrrlScientist. Check it out at:

http://www.theguardian.com/science/grrlscientist/2015/sep/16/predictable-evolution-bad-news-for-toads-good-news-for-their-predators

and share it if you like it!

Widespread convergence in toxin resistance by predictable molecular evolution

Goanna 32_with blue flowers smallCheck out our new paper in PNAS!

http://www.pnas.org/content/early/2015/09/02/1511706112.abstract?sid=ecdba96d-5537-4518-b7cc-cad430a72ba0

https://www.newscientist.com/article/dn28138-resistance-to-toad-toxin-shows-evolution-can-repeat-itself/evolution-can-repeat-itself/

Characterization of antibody V segment diversity in the Tasmanian devil (Sarcophilus harrisii) – now availabe online

Tasmanian devils have highly complex and ancient immunoglobulin light chain variable repertoires. Our article with Kathy Belov just gone online. Check out:

http://www.sciencedirect.com/science/article/pii/S0165242715001750Running devil

Nynke Raven and Kimberly Pinch receive the Student Travel Awards to attend GSA2015

Nynke Raven and Kimberly Pinch receive the prestigious Student Travel Awards to attend GSA2015. We are so proud of you girls!!!  Well done!  http://www.genetics.org.au/2015-conference/BANNER 110414

Evolution of a contagious cancer: epigenetic variation in Devil Facial Tumour Disease featured in Highlights in applied evolutionary biology

Evolutionary Applications’ Highlights has featured our DFTD epigenetics article as one of the exciting papers using evolutionary biology to address questions of practical importance.

Read more about it: http://onlinelibrary.wiley.com/doi/10.1111/eva.12040/abstract

CIE Seminar Series 2015 – Flood and famine: climate-induced collapse of a tropical predator-prey community

 

Thomas MadsenSPEAKER: Prof Thomas Madsen, School of Biological Sciences, University of Wollongong
DATE: Friday, 15th May 2015
LOCATION: Warrnambool Campus, Room G1.01 (Percy Baxter LT)
TIME: 12:00 noon
Seminar will also be video linked to the following campuses: Geelong Campus at Waurn Ponds, Room ka5.303 and Melbourne Campus at Burwood, Room T3.05

ABSTRACT: Will climate change threaten wildlife populations by gradual shifts in mean conditions, or by increased frequency of extreme weather events?

Based on long-term data (from 1991 to 2014), the aim of the present study was to analyze and compare the sensitivity of predator-prey demography to extreme climatic events versus normal, albeit highly variable, annual deviations in climatic conditions in the Australian wet-dry tropics.

From 1991 to 2005, predators (water pythons, Liasis fuscus) and their main prey (dusky rats, Rattus colletti) showed significant climate-driven fluctuations in numbers. These fluctuations were, however, trivial compared to the impact of two massive but brief deluges in 2007 and 2011, which virtually eliminated the dusky rats. The two floods resulted in the pythons experiencing an unprecedented famine in 7 out of the last 8 years causing a massive shift in python demography i.e. a significant reduction in feeding rates, reproductive output, growth rates, relative body mass, survival, mean body length and numbers (from 3173 in 1992 to 96 in 2013).

Our results demonstrate that attempts to predict faunal responses to climate change, even if based on long-term studies, may be doomed to failure. Consequently, biologists may need to confront the uncomfortable truth that increased frequency of brief unpredictable bouts of extreme weather can influence populations far more than gradual deviations in mean climatic conditions.

BIO: Thomas Madsen is firm believer in the importance of conducting long-term field studies in order to make any relevant/significant conclusions about evolutionary processes.

For example, his study on Swedish adders (commenced in 1981 and still running) has revealed the evolutionary significance polyandry. His study water pythons and dusky rats in the Top End of Australia (initiated in 1989 and is still running in collaboration with Beata Ujvari) has revealed the dramatic effects of climate (and climate change) on the population demography of predators-prey interactions in the Australian wet-dry tropics.

Appointments with guest speaker may be made via Graeme Hays